Embryonic MicroRNA-369 Controls Metabolic Splicing Factors and Urges Cellular Reprograming
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منابع مشابه
Embryonic MicroRNA-369 Controls Metabolic Splicing Factors and Urges Cellular Reprograming
Noncoding microRNAs inhibit translation and lower the transcript stability of coding mRNA, however miR-369 s, in aberrant silencing genomic regions, stabilizes target proteins under cellular stress. We found that in vitro differentiation of embryonic stem cells led to chromatin methylation of histone H3K4 at the miR-369 region on chromosome 12qF in mice, which is expressed in embryonic cells an...
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ژورنال
عنوان ژورنال: PLOS ONE
سال: 2015
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0132789